Technology

What is brown adipose tissue?​

Brown adipose tissue (BAT), also called brown fat, is responsible for non-shivering thermogenesis. It is an endocrine organ that plays a key role in glucose and lipid metabolism by consuming fatty acids and glucose and regulating energy homeostasis. Brown fat burns calories into heat.

Having the right quantity of brown fat is very important for human health. Too little or too much BAT results in metabolic imbalance. Having too little of it can lead to obesity and metabolic diseases such as type 2 diabetes. On the other hand, too much BAT results in increased energy expenditure, leading to poor outcomes in patients with cancer and chronic diseases such as chronic obstructive pulmonary disease (COPD), chronic kidney disease, chronic heart failure and HIV-AIDS.

Today, there are no products or methods approved for non-invasive detection of BAT. Such a product would enable patient stratification and predict therapy outcomes.

ImageBAT

Adiposs has developed ImageBAT, the first product that makes brown and beige adipose tissue (BAT) visible with a fast and pain-free CT scan. It enables early detection of body wasting before patients lose body weight. The diagnostic procedure with ImageBAT will be simple, non-invasive and cost-effective: patients will simply drink ImageBAT before their routinely planned medical scan.